Can I update my AI model after 510(k) clearance without a new submission?

Yes, if the change falls within an FDA-authorized PCCP cleared with your device — modifications inside the predetermined protocol can be made without a new 510(k); changes outside it generally still require a new submission. The PCCP is what buys that…

register 09 · Compliance pins· FDA PCCP
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Answer.

Healthcare regulation · FDA PCCP.

Yes, if the change falls within an FDA-authorized PCCP cleared with your device — modifications inside the predetermined protocol can be made without a new 510(k); changes outside it generally still require a new submission. The PCCP is what buys that flexibility. Planisphere helps by producing reproducible drift evidence showing whether updates stayed within the plan's bounds; the regulatory determination of what needs a new submission is FDA's and your regulatory team's.

Cite-anchor: FDA — Marketing Submission Recommendations for a Predetermined Change Control Plan for AI-Enabled Device Software Functions · Final guidance issued 2024-12-03; Description of Modifications, Modification Protocol, Impact Assessment

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The mark behind the answer.

FDA PCCP can require evidence around clinical workflows, ePHI boundaries, change control, or patient-impacting decisions…

Predetermined Change Control Plan · drift-bounded model updates.

→ Full reference for FDA PCCP

Prepare evidence for FDA PCCP review.

First evidence record within 21 days of access · re-runs in a single business day. Planisphere measures model behaviour and emits a reproducible, sha-pinned record — it does not certify, file, or give legal advice.